2021

Metabolites as drivers and targets in Rheumatoid Arthritis.

Hanlon MM, Canavan M, Barker BE, Fearon U.Clin Exp Immunol. 2021 Nov 27

Functionally Mature CD1c⁺ Dendritic Cells Preferentially Accumulate in the Inflammatory Arthritis Synovium.

Canavan M, Marzaioli V, Bhargava V, Nagpal S, Gallagher P, Hurson C, Mullan R, Veale DJ, Fearon U.

Front Immunol. 2021 Oct 7

Loss of balance between protective and pro-inflammatory synovial tissue T-cell polyfunctionality predates clinical onset of rheumatoid arthritis.

Floudas A, Neto N, Orr C, Canavan M, Gallagher P, Hurson C, Monaghan MG, Nagpar S, Mullan RH, Veale DJ, Fearon U.

Ann Rheum Dis. 2021 Oct 1

Targeting JAK-STAT Signalling Alters PsA Synovial Fibroblast Pro-Inflammatory and Metabolic Function.

O’Brien A, Hanlon MM, Marzaioli V, Wade SC, Flynn K, Fearon U, Veale DJ.

Front Immunol. 2021 Jun 24

The effects of alcohol consumption and its associations with disease activity among 979 patients with inflammatory arthritis.

Turk M, Murray K, Alammari Y, Gorman A, Young F, Gallagher P, Saber T, Freeman L, Maguire S, O’Shea F, Fearon U, Veale D.

RMD Open. 2021 Apr

ACPA Status Correlates with Differential Immune Profile in Patients with Rheumatoid Arthritis.

Floudas A, Canavan M, McGarry T, Mullan R, Nagpal S, Veale DJ, Fearon U.

Cells. 2021 Mar 14

Missed Opportunity for Targeted Therapeutic Intervention?

Novel, pathogenic B cell population accumulates in the inflamed joint of rheumatoid arthritis patients

Floudas A.

HPN 2021 Mar.

Serum miRNA Signature in Rheumatoid Arthritis and “At-Risk Individuals”

Cunningham CC, Wade S, Floudas A, Orr C, McGarry T, Wade S, Cregan S, Fearon U, Veale DJ.

Front Immunol. 2021 Mar 3.

Arthroscopic Guided Synovial Biopsies.

Orr CK, Vieira-Sousa E, Fonseca JE, Veale D.

Front Med (Lausanne) . 2021 Feb 11

First use of tofacitinib to treat an immune checkpoint inhibitor-induced arthritis.

Murray K, Floudas A, Murray C, Fabre A, Crown J, Fearon U, Veale D.

BMJ Case Rep. 2021 Feb 4.

COVID-19 and rheumatic musculoskeletal disease patients: infection rates, attitudes and medication adherence in an Irish population

Murray K, Quinn S, Turk M, O’Rourke A, Molloy E, O’Neill L, Mongey AB, Fearon U, Veale DJ

Rheumatology (Oxford). 2021 Feb 1.

Rheumatoid arthritis CD14 ⁺ monocytes display metabolic and inflammatory dysfunction, a phenotype that precedes clinical manifestation of disease

McGarry T, Hanlon MM, Marzaioli V, Cunningham CC, Krishna V, Murray K, Hurson C, Gallagher P, Nagpal S, Veale DJ, Fearon U.

Clin Transl Immunology. 2021 Jan 19

Long-term remission and biologic persistence rates: 12-year real-world data.

Murray K, Turk M, Alammari Y, Young F, Gallagher P, Saber T, Fearon U, Veale DJ.

Arthritis Res Ther. 2021 Jan. 13

The PD-1:PD-L1 axis in Inflammatory Arthritis.

Canavan M, Floudas A, Veale DJ, Fearon U.

BMC Rheumatol. 2021 Jan 11.