Enriched Cd141+ DCs in the joint are transcriptionally distinct, activated, and contribute to joint pathogenesis.

Canavan M, Walsh AM, Bhargava V, Wade SM, McGarry T, Marzaioli V, Moran B, Biniecka M, Convery H, Wade S, Orr C, Mullan R, Fletcher JM, Nagpal S, Veale DJ, Fearon U.

JCI Insight. 2018 Dec 6;3(23)

Altered metabolic pathways regulate synovial inflammation in rheumatoid arthritis.

Fearon U, Hanlon MM, Wade SM, Fletcher JM

Clin Exp Immunol. 2018 Oct 25

Altered expression of microRNA-23a in psoriatic arthritis modulates synovial fibroblast pro-inflammatory mechanisms via phosphodiesterase 4B.

Wade SM, Trenkmann M, McGarry T, Canavan M, Marzaioli V, Wade SC, Veale DJ, Fearon U.

J Autoimmun. 2018 Sep 1.

The Utility and Limitations of CRP, ESR and DAS28-CRP in Appraising Disease Activity in Rheumatoid Arthritis

Orr CK, Najm A, Young F, McGarry T, Biniecka M, Fearon U, Veale DJ.

Front Med (Lausanne). 2018 Aug 3;5:185

Interleukin 12 and interleukin 23 play key pathogenic roles in inflammatory and proliferative pathways in giant cell arteritis.

Conway R, O’Neill L, McCarthy GM, Murphy CC, Fabre A, Kennedy S, Veale DJ, Wade SM, Fearon U, Molloy ES.

Ann Rheum Dis. 2018 Aug 10

The pathogenesis of psoriatic arthritis.

Veale DJ, Fearon U.

Lancet. 2018 Jun 2;391(10136):2273-2284

Oxidative stress impairs energy metabolism in primary cells and synovial tissue of patients with rheumatoid arthritis.

Balogh E, Veale DJ, McGarry T, Orr C, Szekanecz Z, Ng CT, Fearon U, Biniecka M.

Arthritis Res Ther. 2018 May 29;20(1):95

JAK-STAT blockade alters synovial bioenergetics, mitochondrial function and pro-inflammatory mediators in Rheumatoid arthritis.

McGarry T, Orr C, Wade S, Biniecka M, Wade S, Gallagher L, Low C, Veale DJ, Fearon U.

Arthritis Rheumatol. 2018 May 23

Ustekinumab for refractory giant cell arteritis: A prospective 52-week trial.

Conway R, O’Neill L, Gallagher P, McCarthy GM, Murphy CC, Veale DJ, Fearon U, Molloy ES.

Semin Arthritis Rheum. 2018 Apr 22

The rationale for Janus kinase inhibitors for the treatment of spondyloarthritis.

Veale DJ, McGonagle D, McInnes IB, Krueger JG, Ritchlin CT, Elewaut D, Kanik KS, Hendrikx T, Berstein G, Hodge J, Telliez JB.

Rheumatology (Oxford). 2018 Apr 3

Hypoxia, oxidative stress and inflammation.

McGarry T, Biniecka M, Veale DJ, Fearon U.

Free Radic Biol Med. 2018 Mar 27

Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression

Guo Y, Walsh AM, Canavan M, Wechalekar MD, Cole S, Yin X, Scott B, Loza M, Orr C, McGarry T, Bombardieri M, Humby F, Proudman SM, Pitzalis C, Smith MD, Friedman JR, Anderson I, Madakamutil L, Veale DJ, Fearon U, Nagpal S.

PLoS One. 2018 Feb 28;13(2):e0192704